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Proper control of R‐loop homeostasis is required for maintenance of gene expression and neuronal function during aging

Age‐related loss of cellular function and increased cell death are characteristic hallmarks of aging. While defects in gene expression and RNA metabolism have been linked with age‐associated human neuropathies, it is not clear how the changes that occur in aging neurons contribute to loss of gene ex...

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Detalles Bibliográficos
Autores principales: Jauregui‐Lozano, Juan, Escobedo, Spencer, Easton, Alyssa, Lanman, Nadia A., Weake, Vikki M., Hall, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844117/
https://www.ncbi.nlm.nih.gov/pubmed/35048512
http://dx.doi.org/10.1111/acel.13554