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Sex‐ and strain‐specific effects of mitochondrial uncoupling on age‐related metabolic diseases in high‐fat diet‐fed mice

Mild uncoupling of oxidative phosphorylation is an intrinsic property of all mitochondria and may have evolved to protect cells against the production of damaging reactive oxygen species. Therefore, compounds that enhance mitochondrial uncoupling are potentially attractive anti‐aging therapies; howe...

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Detalles Bibliográficos
Autores principales: Goedeke, Leigh, Murt, Kelsey N., Di Francesco, Andrea, Camporez, João Paulo, Nasiri, Ali R., Wang, Yongliang, Zhang, Xian‐Man, Cline, Gary W., de Cabo, Rafael, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844126/
https://www.ncbi.nlm.nih.gov/pubmed/35088525
http://dx.doi.org/10.1111/acel.13539