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Sex‐ and strain‐specific effects of mitochondrial uncoupling on age‐related metabolic diseases in high‐fat diet‐fed mice
Mild uncoupling of oxidative phosphorylation is an intrinsic property of all mitochondria and may have evolved to protect cells against the production of damaging reactive oxygen species. Therefore, compounds that enhance mitochondrial uncoupling are potentially attractive anti‐aging therapies; howe...
Autores principales: | Goedeke, Leigh, Murt, Kelsey N., Di Francesco, Andrea, Camporez, João Paulo, Nasiri, Ali R., Wang, Yongliang, Zhang, Xian‐Man, Cline, Gary W., de Cabo, Rafael, Shulman, Gerald I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844126/ https://www.ncbi.nlm.nih.gov/pubmed/35088525 http://dx.doi.org/10.1111/acel.13539 |
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