The low abundance of CpG in the SARS-CoV-2 genome is not an evolutionarily signature of ZAP

The zinc finger antiviral protein (ZAP) is known to restrict viral replication by binding to the CpG rich regions of viral RNA, and subsequently inducing viral RNA degradation. This enzyme has recently been shown to be capable of restricting SARS-CoV-2. These data have led to the hypothesis that the...

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Detalles Bibliográficos
Autores principales: Afrasiabi, Ali, Alinejad-Rokny, Hamid, Khosh, Azad, Rahnama, Mostafa, Lovell, Nigel, Xu, Zhenming, Ebrahimi, Diako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844275/
https://www.ncbi.nlm.nih.gov/pubmed/35165300
http://dx.doi.org/10.1038/s41598-022-06046-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844275/
https://www.ncbi.nlm.nih.gov/pubmed/35165300
http://dx.doi.org/10.1038/s41598-022-06046-5

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