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The low abundance of CpG in the SARS-CoV-2 genome is not an evolutionarily signature of ZAP
The zinc finger antiviral protein (ZAP) is known to restrict viral replication by binding to the CpG rich regions of viral RNA, and subsequently inducing viral RNA degradation. This enzyme has recently been shown to be capable of restricting SARS-CoV-2. These data have led to the hypothesis that the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844275/ https://www.ncbi.nlm.nih.gov/pubmed/35165300 http://dx.doi.org/10.1038/s41598-022-06046-5 |