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Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI

Sepsis-induced AKI (acute kidney injury) is considered an inflammation-related disease with high mortality. LPS-induced (Lipopolysaccharide) TLR4-NFκB pathway activation plays an important role in sepsis-induced AKI. Pyroptosis closely associated with inflammation response includes inflammasome form...

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Detalles Bibliográficos
Autores principales: Li, Tianlong, Sun, Haibin, Li, Yiming, Su, Lianjiu, Jiang, Jun, Liu, Ye, Jiang, Nanhui, Huang, Rong, Zhang, Jiahao, Peng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844278/
https://www.ncbi.nlm.nih.gov/pubmed/35165294
http://dx.doi.org/10.1038/s41420-022-00859-z