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Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI
Sepsis-induced AKI (acute kidney injury) is considered an inflammation-related disease with high mortality. LPS-induced (Lipopolysaccharide) TLR4-NFκB pathway activation plays an important role in sepsis-induced AKI. Pyroptosis closely associated with inflammation response includes inflammasome form...
Autores principales: | Li, Tianlong, Sun, Haibin, Li, Yiming, Su, Lianjiu, Jiang, Jun, Liu, Ye, Jiang, Nanhui, Huang, Rong, Zhang, Jiahao, Peng, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844278/ https://www.ncbi.nlm.nih.gov/pubmed/35165294 http://dx.doi.org/10.1038/s41420-022-00859-z |
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