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High-dimensional functional phenotyping of preclinical human CAR T cells using mass cytometry

Here, we present a comprehensive protocol for the generation and functional characterization of chimeric antigen receptor (CAR) T cells and their products by mass cytometry in a reproducible and scalable manner. We describe the production of CAR T cells from human peripheral blood mononuclear cells....

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Detalles Bibliográficos
Autores principales: Michelozzi, Ilaria M., Sufi, Jahangir, Adejumo, Thomas A., Amrolia, Persis J., Tape, Christopher J., Giustacchini, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844283/
https://www.ncbi.nlm.nih.gov/pubmed/35199038
http://dx.doi.org/10.1016/j.xpro.2022.101174