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High-dimensional functional phenotyping of preclinical human CAR T cells using mass cytometry
Here, we present a comprehensive protocol for the generation and functional characterization of chimeric antigen receptor (CAR) T cells and their products by mass cytometry in a reproducible and scalable manner. We describe the production of CAR T cells from human peripheral blood mononuclear cells....
Autores principales: | Michelozzi, Ilaria M., Sufi, Jahangir, Adejumo, Thomas A., Amrolia, Persis J., Tape, Christopher J., Giustacchini, Alice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844283/ https://www.ncbi.nlm.nih.gov/pubmed/35199038 http://dx.doi.org/10.1016/j.xpro.2022.101174 |
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