The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) still ranks among the top cancers worldwide with high incidence and mortality. Due to abnormal activation of the PI3K/AKT/mTOR signalling pathway in HCC, targeting this pathway represents a potential therapeutic strategy. NVP-BEZ235 is a novel dual-targeted ATP-competi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yao, Miao, Xiaolong, Jiang, Yuancong, Wu, Zelai, Zhu, Xuhang, Liu, Han, Wu, Xiaoying, Cai, Jinzhen, Ding, Xianfeng, Gong, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844296/
https://www.ncbi.nlm.nih.gov/pubmed/35165269
http://dx.doi.org/10.1038/s41419-022-04583-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844296/
https://www.ncbi.nlm.nih.gov/pubmed/35165269
http://dx.doi.org/10.1038/s41419-022-04583-5

Ejemplares similares