RIPK1-RIPK3 mediates myocardial fibrosis in type 2 diabetes mellitus by impairing autophagic flux of cardiac fibroblasts

Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are critical regulators of programmed necrosis or necroptosis. However, the role of the RIPK1/RIPK3 signaling pathway in myocardial fibrosis and related diabetic cardiomyopathy is still unclear. We hypothesized that RIPK1/RIPK3 activation m...

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Detalles Bibliográficos
Autores principales: Qiao, Shigang, Hong, Lei, Zhu, Yongming, Zha, Jun, Wang, An, Qiu, Jia, Li, Wei, Wang, Chen, An, Jianzhong, Zhang, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844355/
https://www.ncbi.nlm.nih.gov/pubmed/35165268
http://dx.doi.org/10.1038/s41419-022-04587-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844355/
https://www.ncbi.nlm.nih.gov/pubmed/35165268
http://dx.doi.org/10.1038/s41419-022-04587-1

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