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Presynaptic NMDA Receptors Influence Ca(2+) Dynamics by Interacting with Voltage-Dependent Calcium Channels during the Induction of Long-Term Depression

Spike-timing-dependent long-term depression (t-LTD) of glutamatergic layer (L)4-L2/3 synapses in developing neocortex requires activation of astrocytes by endocannabinoids (eCBs), which release glutamate onto presynaptic NMDA receptors (preNMDARs). The exact function of preNMDARs in this context is...

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Detalles Bibliográficos
Autores principales: Neubauer, Florian B., Min, Rogier, Nevian, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844386/
https://www.ncbi.nlm.nih.gov/pubmed/35178084
http://dx.doi.org/10.1155/2022/2900875