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Presynaptic NMDA Receptors Influence Ca(2+) Dynamics by Interacting with Voltage-Dependent Calcium Channels during the Induction of Long-Term Depression
Spike-timing-dependent long-term depression (t-LTD) of glutamatergic layer (L)4-L2/3 synapses in developing neocortex requires activation of astrocytes by endocannabinoids (eCBs), which release glutamate onto presynaptic NMDA receptors (preNMDARs). The exact function of preNMDARs in this context is...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844386/ https://www.ncbi.nlm.nih.gov/pubmed/35178084 http://dx.doi.org/10.1155/2022/2900875 |