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Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

The prevalence of somatic insulinopathies, like metabolic syndrome (MetS), obesity, and type 2 diabetes mellitus (T2DM), is higher in Alzheimer’s disease (AD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD). Dysregulation of insulin signalling has been implicated in these ne...

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Detalles Bibliográficos
Autores principales: Fanelli, Giuseppe, Franke, Barbara, De Witte, Ward, Ruisch, I. Hyun, Haavik, Jan, van Gils, Veerle, Jansen, Willemijn J., Vos, Stephanie J. B., Lind, Lars, Buitelaar, Jan K., Banaschewski, Tobias, Dalsgaard, Søren, Serretti, Alessandro, Mota, Nina Roth, Poelmans, Geert, Bralten, Janita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844407/
https://www.ncbi.nlm.nih.gov/pubmed/35165256
http://dx.doi.org/10.1038/s41398-022-01817-0