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De novo serine synthesis regulates chondrocyte proliferation during bone development and repair
The majority of the mammalian skeleton is formed through endochondral ossification starting from a cartilaginous template. Cartilage cells, or chondrocytes, survive, proliferate and synthesize extracellular matrix in an avascular environment, but the metabolic requirements for these anabolic process...
Autores principales: | Stegen, Steve, Loopmans, Shauni, Stockmans, Ingrid, Moermans, Karen, Carmeliet, Peter, Carmeliet, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844408/ https://www.ncbi.nlm.nih.gov/pubmed/35165259 http://dx.doi.org/10.1038/s41413-021-00185-7 |
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