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Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions

To form functional kinetochores, CENP-C and CENP-T independently recruit the KMN (Knl1C, Mis12C, and Ndc80C) network onto the kinetochores. To clarify the functions of the KMN network on CENP-T, we evaluated its roles in chicken DT40 cell lines lacking the CENP-C-KMN network interaction. By analyzin...

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Detalles Bibliográficos
Autores principales: Takenoshita, Yusuke, Hara, Masatoshi, Fukagawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844409/
https://www.ncbi.nlm.nih.gov/pubmed/35165266
http://dx.doi.org/10.1038/s41467-022-28403-8