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Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity

Cell-based immunotherapies can provide safe and effective treatments for various disorders including autoimmunity, cancer, and excessive proinflammatory events in sepsis or viral infections. However, to achieve this goal there is a need for deeper understanding of mechanisms of the intercellular int...

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Detalles Bibliográficos
Autores principales: Piekarska, Karolina, Urban-Wójciuk, Zuzanna, Kurkowiak, Małgorzta, Pelikant-Małecka, Iwona, Schumacher, Adriana, Sakowska, Justyna, Spodnik, Jan Henryk, Arcimowicz, Łukasz, Zielińska, Hanna, Tymoniuk, Bogusław, Renkielska, Alicja, Siebert, Janusz, Słomińska, Ewa, Trzonkowski, Piotr, Hupp, Ted, Marek-Trzonkowska, Natalia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844425/
https://www.ncbi.nlm.nih.gov/pubmed/35165293
http://dx.doi.org/10.1038/s41467-022-28338-0