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Maternal Low-Protein Diet Deregulates DNA Repair and DNA Replication Pathways in Female Offspring Mammary Gland Leading to Increased Chemically Induced Rat Carcinogenesis in Adulthood

Studies have shown that maternal malnutrition, especially a low-protein diet (LPD), plays a key role in the developmental mechanisms underlying mammary cancer programming in female offspring. However, the molecular pathways associated with this higher susceptibility are still poorly understood. Thus...

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Detalles Bibliográficos
Autores principales: Zapaterini, Joyce R., Fonseca, Antonio R. B., Bidinotto, Lucas T., Colombelli, Ketlin T., Rossi, André L. D., Kass, Laura, Justulin, Luis A., Barbisan, Luis F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844450/
https://www.ncbi.nlm.nih.gov/pubmed/35178394
http://dx.doi.org/10.3389/fcell.2021.756616