K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, with overall long-term survival rates of ∼65-70%. Thus, additional molecular insights and representative models are critical for identifying and evaluating new treatment modalities. Using MyoD-Cre-mediated introduction of mut...

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Detalles Bibliográficos
Autores principales: Nakahata, Kengo, Simons, Brian W., Pozzo, Enrico, Shuck, Ryan, Kurenbekova, Lyazat, Prudowsky, Zachary, Dholakia, Kshiti, Coarfa, Cristian, Patel, Tajhal D., Donehower, Lawrence A., Yustein, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844455/
https://www.ncbi.nlm.nih.gov/pubmed/35174853
http://dx.doi.org/10.1242/dmm.049004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844455/
https://www.ncbi.nlm.nih.gov/pubmed/35174853
http://dx.doi.org/10.1242/dmm.049004

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