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RAS-mediated tumor stress adaptation and the targeting opportunities it presents

Cellular stress is known to function in synergistic cooperation with oncogenic mutations during tumorigenesis to drive cancer progression. Oncogenic RAS is a strong inducer of a variety of pro-tumorigenic cellular stresses, and also enhances the ability of cells to tolerate these stresses through mu...

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Detalles Bibliográficos
Autores principales: Redding, Alexandra, Aplin, Andrew E., Grabocka, Elda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844456/
https://www.ncbi.nlm.nih.gov/pubmed/35147163
http://dx.doi.org/10.1242/dmm.049280