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RAS-mediated tumor stress adaptation and the targeting opportunities it presents
Cellular stress is known to function in synergistic cooperation with oncogenic mutations during tumorigenesis to drive cancer progression. Oncogenic RAS is a strong inducer of a variety of pro-tumorigenic cellular stresses, and also enhances the ability of cells to tolerate these stresses through mu...
Autores principales: | Redding, Alexandra, Aplin, Andrew E., Grabocka, Elda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844456/ https://www.ncbi.nlm.nih.gov/pubmed/35147163 http://dx.doi.org/10.1242/dmm.049280 |
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