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Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation

The vertebrate Six1 and Six2 arose by gene duplication from the Drosophila sine oculis and have since diverged in their developmental expression patterns. Both genes are expressed in nephron progenitors of human fetal kidneys, and mutations in SIX1 or SIX2 cause branchio-oto-renal syndrome or renal...

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Detalles Bibliográficos
Autores principales: Xu, Jinshu, Li, Jun, Ramakrishnan, Aarthi, Yan, Hanen, Shen, Li, Xu, Pin-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844495/
https://www.ncbi.nlm.nih.gov/pubmed/35178390
http://dx.doi.org/10.3389/fcell.2022.815249