Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses

Background: Siglec-1 is a macrophage lectin-like receptor that mediates sialic acid-dependent cellular interactions. Its upregulation on macrophages in autoimmune disease was shown previously to promote inflammation through suppressing the expansion of regulatory T cells (Tregs). Here we investigate...

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Detalles Bibliográficos
Autores principales: Wu, Gang, Murugesan, Gavuthami, Nagala, Manjula, McCraw, Alex, Haslam, Stuart M., Dell, Anne, Crocker, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844539/
https://www.ncbi.nlm.nih.gov/pubmed/35224210
http://dx.doi.org/10.12688/wellcomeopenres.16834.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844539/
https://www.ncbi.nlm.nih.gov/pubmed/35224210
http://dx.doi.org/10.12688/wellcomeopenres.16834.1

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