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Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses
Background: Siglec-1 is a macrophage lectin-like receptor that mediates sialic acid-dependent cellular interactions. Its upregulation on macrophages in autoimmune disease was shown previously to promote inflammation through suppressing the expansion of regulatory T cells (Tregs). Here we investigate...
Autores principales: | Wu, Gang, Murugesan, Gavuthami, Nagala, Manjula, McCraw, Alex, Haslam, Stuart M., Dell, Anne, Crocker, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844539/ https://www.ncbi.nlm.nih.gov/pubmed/35224210 http://dx.doi.org/10.12688/wellcomeopenres.16834.1 |
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