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NAFLD indirectly impairs antigen-specific CD8(+) T cell immunity against liver cancer in mice

Non-alcoholic fatty liver disease (NAFLD) has become an important etiology leading to liver cancer. NAFLD alters adaptive T cell immunity and has a profound influence on liver cancer development. However, it is unclear how NAFLD affects tumor antigen-specific T cell response. In this study, we gener...

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Detalles Bibliográficos
Autores principales: McVey, John C., Green, Benjamin L., Ruf, Benjamin, McCallen, Justin D., Wabitsch, Simon, Subramanyam, Varun, Diggs, Laurence P., Heinrich, Bernd, Greten, Tim F., Ma, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844694/
https://www.ncbi.nlm.nih.gov/pubmed/35198900
http://dx.doi.org/10.1016/j.isci.2022.103847