CRISPR/Cas9-induced gene conversion between ATAD3 paralogs

Paralogs and pseudogenes are abundant within the human genome, and can mediate non-allelic homologous recombination (NAHR) or gene conversion events. The ATAD3 locus contains three paralogs situated in tandem, and is therefore prone to NAHR-mediated deletions and duplications associated with severe...

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Detalles Bibliográficos
Autores principales: Yanovsky-Dagan, Shira, Frumkin, Ayala, Lupski, James R., Harel, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844715/
https://www.ncbi.nlm.nih.gov/pubmed/35199044
http://dx.doi.org/10.1016/j.xhgg.2022.100092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844715/
https://www.ncbi.nlm.nih.gov/pubmed/35199044
http://dx.doi.org/10.1016/j.xhgg.2022.100092

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