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A phase I/IIa trial of atorvastatin in Japanese patients with acute Kawasaki disease with coronary artery aneurysm: Study protocol of a multicenter, single-arm, open-label trial

BACKGROUND: Kawasaki disease (KD) is a systemic vasculitis complicated with coronary artery abnormalities (CAAs). Intravenous immunoglobulin reduces the occurrence of CAAs, but significant number of KD patients with CAAs still exists. Thus, new approaches to prevent and attenuate CAAs are warranted....

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Detalles Bibliográficos
Autores principales: Murata, Yo, Isayama, Reina, Imai, Shoko, Shoji, Kensuke, Youndzi, Mizuho, Okada, Mami, Mikami, Masashi, Kobayashi, Shinobu, Urayama, Kevin Y., Kobayashi, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844785/
https://www.ncbi.nlm.nih.gov/pubmed/35198792
http://dx.doi.org/10.1016/j.conctc.2022.100892