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Identifying stem cell numbers and functional heterogeneities during postembryonic organ growth

Uncovering the number of stem cells necessary for organ growth has been challenging in vertebrate systems. Here, we developed a mathematical model characterizing stem cells in the fish gill, an organ displaying non-exhaustive growth. We employ a Markov model, stochastically simulated via an adapted...

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Detalles Bibliográficos
Autores principales: Danciu, Diana-Patricia, Stolper, Julian, Centanin, Lázaro, Marciniak-Czochra, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844824/
https://www.ncbi.nlm.nih.gov/pubmed/35198882
http://dx.doi.org/10.1016/j.isci.2022.103819