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Identifying stem cell numbers and functional heterogeneities during postembryonic organ growth
Uncovering the number of stem cells necessary for organ growth has been challenging in vertebrate systems. Here, we developed a mathematical model characterizing stem cells in the fish gill, an organ displaying non-exhaustive growth. We employ a Markov model, stochastically simulated via an adapted...
Autores principales: | Danciu, Diana-Patricia, Stolper, Julian, Centanin, Lázaro, Marciniak-Czochra, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844824/ https://www.ncbi.nlm.nih.gov/pubmed/35198882 http://dx.doi.org/10.1016/j.isci.2022.103819 |
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