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Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

The organization of the postsynaptic density (PSD), a protein-dense semi-membraneless organelle, is mediated by numerous specific protein–protein interactions (PPIs) which constitute a functional postsynapse. The PSD protein 95 (PSD-95) interacts with a manifold of proteins, including the C-terminal...

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Detalles Bibliográficos
Autores principales: Christensen, Nikolaj Riis, Pedersen, Christian Parsbæk, Sereikaite, Vita, Pedersen, Jannik Nedergaard, Vistrup-Parry, Maria, Sørensen, Andreas Toft, Otzen, Daniel, Teilum, Kaare, Madsen, Kenneth Lindegaard, Strømgaard, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844826/
https://www.ncbi.nlm.nih.gov/pubmed/35198873
http://dx.doi.org/10.1016/j.isci.2022.103808