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Unique B-1 cells specific for both N-pyrrolated proteins and DNA evolve with apolipoprotein E deficiency
Lysine N-pyrrolation, a posttranslational modification, which converts lysine residues to N(ε)-pyrrole-L-lysine, imparts electronegative properties to proteins, causing them to mimic DNA. Apolipoprotein E (apoE) has been identified as a soluble receptor for pyrrolated proteins (pyrP), and accelerate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844855/ https://www.ncbi.nlm.nih.gov/pubmed/35031322 http://dx.doi.org/10.1016/j.jbc.2022.101582 |