Unique B-1 cells specific for both N-pyrrolated proteins and DNA evolve with apolipoprotein E deficiency

Lysine N-pyrrolation, a posttranslational modification, which converts lysine residues to N(ε)-pyrrole-L-lysine, imparts electronegative properties to proteins, causing them to mimic DNA. Apolipoprotein E (apoE) has been identified as a soluble receptor for pyrrolated proteins (pyrP), and accelerate...

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Detalles Bibliográficos
Autores principales: Lim, Sei-Young, Yamaguchi, Kosuke, Itakura, Masanori, Chikazawa, Miho, Matsuda, Tomonari, Uchida, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844855/
https://www.ncbi.nlm.nih.gov/pubmed/35031322
http://dx.doi.org/10.1016/j.jbc.2022.101582

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