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Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems

RNA interference by type III CRISPR systems results in the synthesis of cyclic oligoadenylate (cOA) second messengers, which are known to bind and regulate various CARF domain–containing nuclease receptors. The CARF domain–containing Csa3 family of transcriptional factors associated with the DNA-tar...

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Detalles Bibliográficos
Autores principales: Xia, Pengjun, Dutta, Anirudha, Gupta, Kushol, Batish, Mona, Parashar, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844856/
https://www.ncbi.nlm.nih.gov/pubmed/35038453
http://dx.doi.org/10.1016/j.jbc.2022.101591