Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site

Erythromycin resistance methyltransferases (Erms) confer resistance to macrolide, lincosamide, and streptogramin antibiotics in Gram-positive bacteria and mycobacteria. Although structural information for ErmAM, ErmC, and ErmE exists from Gram-positive bacteria, little is known about the Erms in myc...

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Detalles Bibliográficos
Autores principales: Goh, Boon Chong, Xiang, Xinyu, Lescar, Julien, Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844858/
https://www.ncbi.nlm.nih.gov/pubmed/35007529
http://dx.doi.org/10.1016/j.jbc.2022.101571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844858/
https://www.ncbi.nlm.nih.gov/pubmed/35007529
http://dx.doi.org/10.1016/j.jbc.2022.101571

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