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Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site

Erythromycin resistance methyltransferases (Erms) confer resistance to macrolide, lincosamide, and streptogramin antibiotics in Gram-positive bacteria and mycobacteria. Although structural information for ErmAM, ErmC, and ErmE exists from Gram-positive bacteria, little is known about the Erms in myc...

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Detalles Bibliográficos
Autores principales:	Goh, Boon Chong, Xiang, Xinyu, Lescar, Julien, Dedon, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844858/ https://www.ncbi.nlm.nih.gov/pubmed/35007529 http://dx.doi.org/10.1016/j.jbc.2022.101571

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