Leukocyte activation primes fibrinogen for proteolysis by mitochondrial oxidative stress

Critical illness leads to rapid fibrinogen consumption, hyperfibrinolysis, and coagulopathy that exacerbates bleeding and increases mortality. Immune cell activation and inflammation are associated with coagulopathy after injury but play an undetermined role. We performed high dimensional immunophen...

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Detalles Bibliográficos
Autores principales: Han, Chang Yeop, Pichon, Trey J., Wang, Xu, Ringgold, Kristyn M., St John, Alexander E., Stern, Susan A., White, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844908/
https://www.ncbi.nlm.nih.gov/pubmed/35158163
http://dx.doi.org/10.1016/j.redox.2022.102263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844908/
https://www.ncbi.nlm.nih.gov/pubmed/35158163
http://dx.doi.org/10.1016/j.redox.2022.102263

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