Cargando…
Leukocyte activation primes fibrinogen for proteolysis by mitochondrial oxidative stress
Critical illness leads to rapid fibrinogen consumption, hyperfibrinolysis, and coagulopathy that exacerbates bleeding and increases mortality. Immune cell activation and inflammation are associated with coagulopathy after injury but play an undetermined role. We performed high dimensional immunophen...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844908/ https://www.ncbi.nlm.nih.gov/pubmed/35158163 http://dx.doi.org/10.1016/j.redox.2022.102263 |