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Multiple Regulatory Mechanisms Control the Production of CmrRST, an Atypical Signal Transduction System in Clostridioides difficile

Clostridioides difficile, an intestinal pathogen and leading cause of nosocomial infection, exhibits extensive phenotypic heterogeneity through phase variation. The signal transduction system CmrRST, which encodes two response regulators (CmrR and CmrT) and a sensor kinase (CmrS), impacts C. diffici...

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Detalles Bibliográficos
Autores principales: Garrett, Elizabeth M., Mehra, Anchal, Sekulovic, Ognjen, Tamayo, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844915/
https://www.ncbi.nlm.nih.gov/pubmed/35164558
http://dx.doi.org/10.1128/mbio.02969-21