Cargando…

Molecular Basis of Rhodomyrtone Resistance in Staphylococcus aureus

Rhodomyrtone (Rom) is a plant-derived broad-spectrum antibiotic active against many Gram-positive pathogens. A single point mutation in the regulatory farR gene (farR*) confers resistance to Rom in Staphylococcus aureus (RomR). The mutation in farR* alters the activity of the regulator, FarR*, in su...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Li, Matsuo, Miki, Calderón, Carlos, Fan, Sook-Ha, Ammanath, Aparna Viswanathan, Fu, Xiaoqing, Li, Ningna, Luqman, Arif, Ullrich, Marvin, Herrmann, Florian, Maier, Martin, Cheng, Anchun, Zhang, Fajun, Oesterhelt, Filipp, Lämmerhofer, Michael, Götz, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844917/
https://www.ncbi.nlm.nih.gov/pubmed/35164566
http://dx.doi.org/10.1128/mbio.03833-21