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Molecular Basis of Rhodomyrtone Resistance in Staphylococcus aureus
Rhodomyrtone (Rom) is a plant-derived broad-spectrum antibiotic active against many Gram-positive pathogens. A single point mutation in the regulatory farR gene (farR*) confers resistance to Rom in Staphylococcus aureus (RomR). The mutation in farR* alters the activity of the regulator, FarR*, in su...
Autores principales: | Huang, Li, Matsuo, Miki, Calderón, Carlos, Fan, Sook-Ha, Ammanath, Aparna Viswanathan, Fu, Xiaoqing, Li, Ningna, Luqman, Arif, Ullrich, Marvin, Herrmann, Florian, Maier, Martin, Cheng, Anchun, Zhang, Fajun, Oesterhelt, Filipp, Lämmerhofer, Michael, Götz, Friedrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844917/ https://www.ncbi.nlm.nih.gov/pubmed/35164566 http://dx.doi.org/10.1128/mbio.03833-21 |
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