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Interaction Tolerance Detection Test for Understanding the Killing Efficacy of Directional Antibiotic Combinations

Combination treatments are commonly prescribed for enhancing drug efficacy, as well as for preventing the evolution of resistance. The interaction between drugs is typically evaluated near the MIC, using growth rate as a measure of treatment efficacy. However, for infections in which the killing act...

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Detalles Bibliográficos
Autores principales: Liu, Jia-Feng, Gefen, Orit, Zhang, Zi-Yin, Liu, Min-Min, Bar-Meir, Maskit, Balaban, Nathalie Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844919/
https://www.ncbi.nlm.nih.gov/pubmed/35164563
http://dx.doi.org/10.1128/mbio.00004-22