Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) extensively N-glycosylates its spike proteins, which are necessary for host cell invasion and the target of both vaccines and immunotherapies. These N-glycans are predicted to modulate spike binding to the host receptor by stabilizing its...

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Detalles Bibliográficos
Autores principales: Casas-Sanchez, Aitor, Romero-Ramirez, Alessandra, Hargreaves, Eleanor, Ellis, Cameron C., Grajeda, Brian I., Estevao, Igor L., Patterson, Edward I., Hughes, Grant L., Almeida, Igor C., Zech, Tobias, Acosta-Serrano, Álvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844921/
https://www.ncbi.nlm.nih.gov/pubmed/35164559
http://dx.doi.org/10.1128/mbio.03718-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844921/
https://www.ncbi.nlm.nih.gov/pubmed/35164559
http://dx.doi.org/10.1128/mbio.03718-21

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