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Augmentation of the Riboflavin-Biosynthetic Pathway Enhances Mucosa-Associated Invariant T (MAIT) Cell Activation and Diminishes Mycobacterium tuberculosis Virulence

Mucosa-associated invariant T (MAIT) cells play a critical role in antimicrobial defense. Despite increased understanding of their mycobacterial ligands and the clinical association of MAIT cells with tuberculosis (TB), their function in protection against Mycobacterium tuberculosis infection remain...

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Detalles Bibliográficos
Autores principales: Dey, Ruchi Jain, Dey, Bappaditya, Harriff, Melanie, Canfield, Elizabeth T., Lewinsohn, David M., Bishai, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844931/
https://www.ncbi.nlm.nih.gov/pubmed/35164552
http://dx.doi.org/10.1128/mbio.03865-21