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Signal Peptidase-Mediated Cleavage of the Anti-σ Factor RsiP at Site 1 Controls σ(P) Activation and β-Lactam Resistance in Bacillus thuringiensis
In Bacillus thuringiensis, β-lactam antibiotic resistance is controlled by the extracytoplasmic function (ECF) σ factor σ(P). σ(P) activity is inhibited by the anti-σ factor RsiP. In the presence of β-lactam antibiotics, RsiP is degraded and σ(P) is activated. Previous work found that RsiP degradati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Microbiology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844934/ https://www.ncbi.nlm.nih.gov/pubmed/35164554 http://dx.doi.org/10.1128/mbio.03707-21 |