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Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication

Emerging mutations in the SARS-CoV-2 genome pose a challenge for vaccine development and antiviral therapy. The antiviral efficacy of Azadirachta indica bark extract (NBE) was assessed against SARS-CoV-2 and m-CoV-RSA59 infection. Effects of in vivo intranasal or oral NBE administration on viral loa...

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Detalles Bibliográficos
Autores principales: Sarkar, Lucky, Oko, Lauren, Gupta, Soham, Bubak, Andrew N., Das, Bishnu, Gupta, Parna, Safiriyu, Abass Alao, Singhal, Chirag, Neogi, Ujjwal, Bloom, David, Banerjee, Arup, Mahalingam, Ravi, Cohrs, Randall J., Koval, Michael, Shindler, Kenneth S., Pal, Debnath, Nagel, Maria, Sarma, Jayasri Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844965/
https://www.ncbi.nlm.nih.gov/pubmed/35219218
http://dx.doi.org/10.1016/j.virol.2022.01.002