A switch from α‐helical to β‐strand conformation during co‐translational protein folding

Cellular proteins begin to fold as they emerge from the ribosome. The folding landscape of nascent chains is not only shaped by their amino acid sequence but also by the interactions with the ribosome. Here, we combine biophysical methods with cryo‐EM structure determination to show that folding of...

Descripción completa

Detalles Bibliográficos
Autores principales: Agirrezabala, Xabier, Samatova, Ekaterina, Macher, Meline, Liutkute, Marija, Maiti, Manisankar, Gil‐Carton, David, Novacek, Jiri, Valle, Mikel, Rodnina, Marina V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844987/
https://www.ncbi.nlm.nih.gov/pubmed/34994471
http://dx.doi.org/10.15252/embj.2021109175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844987/
https://www.ncbi.nlm.nih.gov/pubmed/34994471
http://dx.doi.org/10.15252/embj.2021109175

Ejemplares similares