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Periodontal Infection Aggravates C1q-Mediated Microglial Activation and Synapse Pruning in Alzheimer’s Mice

Periodontitis is a dysbiotic infectious disease that leads to the destruction of tooth supporting tissues. There is increasing evidence that periodontitis may affect the development and severity of Alzheimer’s disease (AD). However, the mechanism(s) by which periodontal infection impacts the neurode...

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Detalles Bibliográficos
Autores principales: Hao, Xiaoxiao, Li, Zhaofei, Li, Wei, Katz, Jannet, Michalek, Suzanne M., Barnum, Scott R., Pozzo-Miller, Lucas, Saito, Takashi, Saido, Takaomi C., Wang, Qin, Roberson, Erik D., Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845011/
https://www.ncbi.nlm.nih.gov/pubmed/35178049
http://dx.doi.org/10.3389/fimmu.2022.816640