Picomolar-sensitive β-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulated π-elongated dioxaborine-dyes

The pathological origin of Alzheimer's disease (AD) is still shrouded in mystery, despite intensive worldwide research efforts. The selective visualization of β-amyloid (Aβ), the most abundant proteinaceous deposit in AD, is pivotal to reveal AD pathology. To date, several small-molecule fluoro...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Jusung, Verwilst, Peter, Aziz, Hira, Shin, Jinwoo, Lim, Sungsu, Kim, Ilwha, Kim, Yun Kyung, Kim, Jong Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845109/
https://www.ncbi.nlm.nih.gov/pubmed/35224305
http://dx.doi.org/10.1016/j.bioactmat.2021.10.047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845109/
https://www.ncbi.nlm.nih.gov/pubmed/35224305
http://dx.doi.org/10.1016/j.bioactmat.2021.10.047

Ejemplares similares