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Picomolar-sensitive β-amyloid fibril fluorophores by tailoring the hydrophobicity of biannulated π-elongated dioxaborine-dyes
The pathological origin of Alzheimer's disease (AD) is still shrouded in mystery, despite intensive worldwide research efforts. The selective visualization of β-amyloid (Aβ), the most abundant proteinaceous deposit in AD, is pivotal to reveal AD pathology. To date, several small-molecule fluoro...
Autores principales: | An, Jusung, Verwilst, Peter, Aziz, Hira, Shin, Jinwoo, Lim, Sungsu, Kim, Ilwha, Kim, Yun Kyung, Kim, Jong Seung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845109/ https://www.ncbi.nlm.nih.gov/pubmed/35224305 http://dx.doi.org/10.1016/j.bioactmat.2021.10.047 |
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