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Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19

Immunopathology occurs in the lung and spleen in fatal coronavirus disease (COVID-19), involving monocytes/macrophages and plasma cells. Antiinflammatory therapy reduces mortality, but additional therapeutic targets are required. We aimed to gain mechanistic insight into COVID-19 immunopathology by...

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Detalles Bibliográficos
Autores principales: Russell, Clark D., Valanciute, Asta, Gachanja, Naomi N., Stephen, Jillian, Penrice-Randal, Rebekah, Armstrong, Stuart D., Clohisey, Sara, Wang, Bo, Al Qsous, Wael, Wallace, William A., Oniscu, Gabriel C., Stevens, Jo, Harrison, David J., Dhaliwal, Kevin, Hiscox, Julian A., Baillie, J. Kenneth, Akram, Ahsan R., Dorward, David A., Lucas, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845132/
https://www.ncbi.nlm.nih.gov/pubmed/34710339
http://dx.doi.org/10.1165/rcmb.2021-0358OC