CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand

INTRODUCTION: The minor allele of a missense variant, rs373863828, in CREBRF is associated with higher body mass index (BMI), lower fasting glucose, and lower odds of type 2 diabetes. rs373863828 is common in Pacific Island populations (minor allele frequency (MAF) 0.096–0.259) but rare in non-Pacif...

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Detalles Bibliográficos
Autores principales: Russell, Emily M, Carlson, Jenna C, Krishnan, Mohanraj, Hawley, Nicola L, Sun, Guangyun, Cheng, Hong, Naseri, Take, Reupena, Muagututi‘a Sefuiva, Viali, Satupa‘itea, Tuitele, John, Major, Tanya J, Miljkovic, Iva, Merriman, Tony R, Deka, Ranjan, Weeks, Daniel E, McGarvey, Stephen T, Minster, Ryan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845200/
https://www.ncbi.nlm.nih.gov/pubmed/35144939
http://dx.doi.org/10.1136/bmjdrc-2021-002275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845200/
https://www.ncbi.nlm.nih.gov/pubmed/35144939
http://dx.doi.org/10.1136/bmjdrc-2021-002275

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